PUBLICATIONS
At UCLA
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Prior to UCLA
8. Li, C.; Stražar, M.; Mohamed, A.; Pacheco, J. A.; Walker, R. L.; Lebar, T.; Zhao, S.; Lockart, J.; Dame, A.; Thurimella, K.; Jeanfavre, S.; Brown, E.M.; Ang, Q. A.; Berdy, B.; Sergio, D.; Ivernizzi, R.; Tinoco, A.; Pischany, G.; Vasan, R. S.; Balskus, E.P.; Huttenhower, C.; Vlamakis, H.; Clish, C.; Shaw, S. Y.; Plichta, D.; Xavier, R. “Gut microbiome and metabolome profiling in Framingham Heart Study reveals cholesterol-metabolizing bacteria linked with lower cardiovascular risk” Cell 2024, 187, 1834–1852.e19.
DOI: 10.1016/j.cell.2024.03.014. Link.
7. Nam, D.†; Tinoco, A.†; Shen, Z.; Adukure, R.; Sreenilayam, G.; Khare, S. D.; Fasan, R. “Enantioselective Synthesis of α-Trifluoromethyl Amines via Biocatalytic N−H Bond Insertion with Acceptor-Acceptor Carbenes.” Journal of the American Chemical Society 2022 144, 2590−2602.
DOI: 10.1021/jacs.1c10750. Link.
*Highlighted in: Synfacts 2022, 18, 543; Synfacts 2022, 18, 819.
6. Tinoco, A.†; Wei, Y.†; Bacik, J. P.; Carminati, D. M.; Moore, E.J.; Ando, N.; Zhang, Y.; Fasan, R. “Origin of High Stereocontrol in Olefin Cyclopropanation Catalyzed by an Engineered Carbene Transferase.” ACS Catalysis 2019, 9, 1514–1524.
DOI: 10.1021/acscatal.8b04073. Link.
5. Vargas, D. A.; Tinoco, A.; Tyagi, V.; Fasan, R. “Myoglobin-Catalyzed C−H Functionalization of Unprotected Indoles.” Angewandte Chemie International Edition 2018, 57, 9911–9915.
DOI: 10.1002/anie.201804779. Link.
4. Wei, Y.; Tinoco, A.; Steck, V.; Fasan, R.; Zhang, Y. “Cyclopropanations via Heme Carbenes: Basic Mechanism and Effects of Carbene Substituent, Protein Axial Ligand, and Porphyrin Substitution.” Journal of the American Chemical Society 2018, 140, 1649–1662.
DOI: 10.1021/jacs.7b09171. Link.
3. Tinoco, A.; Steck, V.; Tyagi, V.; Fasan, R. “Highly Diastereo- and Enantioselective Synthesis of Trifluoromethyl-Substituted Cyclopropanes via Myoglobin-Catalyzed Transfer of Trifluoromethylcarbene.” Journal of the American Chemical Society 2017, 139, 5293–5296.
DOI: 10.1021/jacs.7b00768. Link.
*Highlighted in: Chem. Eng. News 2017, 95, 5; Synfacts 2017, 13, 762; J. Am. Chem. Soc. 2017, 139, 14331.
2. Tyagi, V.; Sreenilayam, G.; Bajaj, P.; Tinoco, A.; Fasan, R. “Biocatalytic Synthesis of Allylic and Allenyl Sulfides via a Myoglobin-Catalyzed Doyle-Kirmse Reaction.” Angewandte Chemie International Edition 2016, 55, 13562–13566.
DOI: 10.1002/anie.201607278. Link.
1.Culver, S. P.; Greaney, M. J.; Tinoco, A.; Brutchey, R. L. “Low-Temperature Synthesis of Homogeneous Solid Solutions of Scheelite-Structured Ca1–xSrxWO4 and Sr1–xBaxWO4 Nanocrystals.” Dalton Transactions 2015, 44, 15042–15048.
DOI: 10.1039/C5DT01722J. Link.